Species: ~ 35.
Geography: western Mexico, Caribbean, Venezuela, eastern Brazil, Amazon, Equador, Peru
- Melocactus x albicephalus Buining & Brederoo 1971 (Brazil)
= nat. hybrid: Melocactus ernestii x Melocactus glaucescens
- Melocactus andianus R. Gruber ex N. P. Taylor 1991 (Columbia, Venezuela)
- Melocactus azureus Buining & Brederoo 1971 (Bahia, Brazil)
- Melocactus bahiensis (Britton & Rose) Lützelburg 1923 (eastern Brazil)
- Melocactus bellavistensis Rauh & Backeberg 1957 (southern Ecuador, northern Peru)
- Melocactus bellavistensis subsp. onychacanthus (F. Ritter) N. P. Taylor 1991
= Melocactus onychacanthus RITTER
- Melocactus caroli-linnaei N. P. Taylor 1991 (Jamaica)
- Melocactus concinnus Buining & Brederoo 1972 (Bahia, Minas Gerais, Brazil)
- Melocactus conoideus Buining & Brederoo 1973 (Bahia, Brazil)
- Melocactus curvispinus Pfeiffer 1837 (Mexico, Peru, Colombia, Venezuela, Caribbean)
- Melocactus deinacanthus Buining & Brederoo 1973 (Bahia, Brazil)
- Melocactus ernesti Vaupel 1920 (Bahia, Brazil)
- Melocactus estevesii P. J. Braun 1989
- Melocactus glaucescens Buining & Brederoo 1972 (Bahia, Brazil)
- Melocactus harlowii (Britton & Rose) Vaupel 1912 (Cuba)
- Melocactus intorus (P. Miller) Urban 1919 (Caribbean)
- Melocactus lanssensianus P. J. Braun 1986
- Melocactus lamairei (Monville ex Lemaire) Miquel ex Lemaire 1840
- Melocactus levitestatus Buining & Brederoo 1973 (Bahia, Minas Gerais, Brazil)
- Melocactus marcacanthos (Salm-Dyck) Link & Otto 1919 (Caribbean)
- Melocactus mantanzanus Léon 1934 (Cuba)
- Melocactus neryi K. Schumann 1901
- Melocactus onychacanthus F. Ritter
= Melocactus bellavistensis subsp. onychacanthus (F. Ritter) N.P.Taylor 1991
- Melocactus oreas Miquel 1840
- Melocactus pachyacanthus Buining & Brederoo 1975 (Bahia, Brazil)
- Melocactus paucispinus G. Heimen & R. Paul 1983 (Bahia, Brazil)
- Melocactus perezassoi Areces 1993 (central Cuba)
- Melocactus peruvianus Vaupel 1913 (Equador, Peru)
- Melocactus praerupticola Areces 2000 (Dominican Republic)
- Melocactus salvadorensis Werdermann 1934 (Bahia, Brazil)
- Melocactus schatzii H. Till & R. Gruber 1982 (Colombia, Venezuela)
- Melocactus smithii (Alexander) Buning ex G. D. Rowley 1976 (Guyana, Brazil)
- Melocactus violaceus Pfeiffer 1835 (Bahia, Minas Gerais, Brazil)
- Melocactus zehntneri (Britton & Rose) Lützelburg 1923 (northeastern Brazil)
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